GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABAA receptor trafficking and social behavior

Abstract Dysfunctional mTOR signaling is associated with the pathogenesis of neurodevelopmental and neuropsychiatric disorders. However, it is unclear what molecular mechanisms and pathogenic mediators are involved and whether mTOR-regulated autophagy continues to be crucial beyond neurodevelopment. Here, we selectively deleted Atg7 in forebrain GABAergic interneurons in adolescent mice and...

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Your daily 6: Grand Canyon tourist dies in fall, video captures brutal killing of bear, teen dies of tapeworm infection in brain – STLtoday.com

Your daily 6: Grand Canyon tourist dies in fall, video captures brutal killing of bear, teen dies of tapeworm infection in brain  STLtoday.com Also trending on your Friday: Trump says Special Olympics will be funded, undercutting Betsy DeVos, Chicago seeks $130K from Smollett for cost of … Source link

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Ofsted warns teachers against ‘gimmicks’ such as Brain Gym | Education

The chief inspector of schools in England has warned teachers and policymakers against resting their hopes on the latest educational gimmicks and urged them instead to focus on getting the basics right. Launching her second annual report as head of Ofsted, Amanda Spielman advised against the likes of Brain...

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