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    Restriction endonucleases are enzymes that

    P. cleave the 5’ terminal nucleotides from duplex DNA molecules

    Q. make sequence – specific cuts in both strands of duplex DNA molecules

    R. Promote circulatization of the duplex DNA molecule by removal of the 5’ terminal nucleotides

    S. generate 3’ hydroxyl and 5’ – phosphate ends in the cut DNA strands

    Options :-

    1. P, Q

    2. P, R

    3. Q, S

    4. P, Q, R, S

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